Cardiac Biomarkers
نویسندگان
چکیده
1950’s: Clinical reports that transaminases released from dying myocytes could be detected via laboratory testing, aiding in the diagnosis of myocardial infarction. The race to define clinical markers to aid in the diagnosis, prognosis, and risk stratification of patients with potential cardiovascular disease begins. Initial serum markers included AST, LDH, total CK and α-hydroxybutyrate. These enzymes are all released in varying amounts by dying myocytes. Lack of sensitivity and specificity for cardiac muscle necrosis fuels continued research.
منابع مشابه
Diagnostic and Prognostic Value of Cardiac Biomarkers in Children with Kawasaki Disease: A State-of-the-Art Review
Kawasaki disease (KD) is characterized as the leading cause of acquired cardiac disease in children. Accurate and timely diagnosis of KD is of high importance for preventing its cardiac complications. However, diagnosis merely based on clinical findings has a number of challenges and, limitations. Therefore, researchers are investigating to find more object...
متن کاملSertraline alters level of adenosine deaminase activity, oxidative stress markers and cardiac biomarkers (homocysteine cardiac troponin I) in rats
The aim of this study is whether oxidative stress markers, homocysteine (Hcy), cardiac troponin I (cTnI) and the activity of adenosine deaminase (ADA) alter following administration of different doses of sertraline. Sixty male Wistar rats were assigned into four groups. Sertraline at doses of 20, 40 and 80 mg / kg / day) were administered to three groups through gastric gavage for 90 days. The ...
متن کاملEvaluation of dysrhythmias and myocardial biomarkers in high and low-yielding dairy cows
BACKGROUND: Cardiovascular system is a very importantorgan that plays a vital role in tissue function. In farm animals,the growth and high milk production depends on function ofcardiovascular system. OBJECTIVES: Cardiovascular health inhigh and low-yielding dairy cows was investigated. METHODS:Fifty 4-year-old high- yielding Holstein dairy cows and fifty 4-year-old low- yielding Holstein dairy ...
متن کاملاندازه گیری بیومارکرهای قلبی بعد از آنژیوپلاستی و ارزش پیش آگهی آن
The importance of cardiac biomarkers in the prognosis of patients with acute coronary syndrome is clear. However, there are some controversies regarding measuring these cardiac biomarkers post angioplasty through percutaneous coronary intervention (PCI). In this study we will review the importance of increased cardiac biomarkers after elective PCI on the prognosis of patients. Also, the definit...
متن کاملCardiac Biomarkers for Early Detection of Cardiac Involvement in Children with Kawasaki Disease: A Cross-Sectional Study
Background: Kawasaki disease (KD) is one of the most prevalent vasculitis diseases in children and can bring about serious cardiovascular complications. Early detection of cardiac involvement in KD can play an essential role in managing and preventing the cardiac sequels. We aimed to evaluate the applicability and diagnostic accuracy of cardiac biomarkers including car...
متن کاملEvaluation of cardiac troponin I, atrial natriuretic peptide and some oxidative/antioxidative biomarkers in the serum and hemolysate of trained Arabian horses after exercise
Background: Limited information existed on performance tests in Iranian Arab horses. Aims: The objective of this study is to investigate time related changes of cardiac troponin I (cTnI), atrial natriuretic peptide (ANP) and oxidative/antioxidant biomarkers in the serum of Arabian horses before and after regular training. Methods: Blood samples were collected from jugular vein of 25 Arabian hor...
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